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Forensic anthropologist Dr. Temperance "Bones" Brennan and cocky F.B.I. Special Agent Seeley Booth build a team to investigate murders. Quite often, there isn't more to examine than rotten flesh or mere bones.
The Portland Police Bureau's Elite Special Crimes Unit is led by Det. Lt. Everett Backstrom, an alcoholic and smoker who is in failing health, but takes on cases in special circumstances.
An Iraq war vet suffers a brain injury that triggers the ability to see connections between seemingly unrelated events, objects or people.
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