When Ed and Al discover the source of the strange disease that has stricken Xenotime, they also find out the history behind the Tringham Brother's father and his involvement with the red water. This news does not please Mugear, who had commissioned the Tringham Brothers to make the Philosopher's Stone. He is determined to stop the real Elric Brothers from interfering with his work, and with the red water he may be able to do it.